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Increased titers of creatinine and urea testify to the pathology of the kidneys and urinary tract. The pathology of the hepatobiliary system is indicated by total bilirubin and its fractions, transaminases, gamma-glutamyl transpeptidase, alkaline phosphatase, etc.

The inflammation of the pancreas is evidenced by blood alpha-amylase. General inflammatory changes are reflected by such analyzes as thymol test and sublimate test, and C-reactive protein, rheumatoid factor, antistreptolysin-O, circulating immune complexes, etc., testify to inflammation in systemic connective tissue disease.